a lot of :许多,大量.【既修饰可数名词,也可以修饰不可数名词】.后接名词、代词或名词词性法语名词性词组.

A lot of people haved done it successfully.

A lot of water has been used up.

a little:有一点有一些.【修是不可数名词】.

a little 少许, 一点

a lot of 很多

Preparing a good breakfast doesn't require a lot of time, just a little planning should do the trick.

a little 不可接可数名词 (要用 a few + 可数名词)

a lot of 可接可数名词, 如 a lot of buildings have been erected last year.